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Infectious Disease: Influenza

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Total 22078 results found since Jan 2013.

Text messages modestly increase influenza vaccination rates and timeliness of vaccination among children and teens at risk of severe influenza
Tuckerman J, Harper K, Sullivan TR, Cuthbert AR, Fereday J, Couper J, et al. Short message service (SMS) reminder nudge for parents and influenza vaccination uptake in children and adolescents with special risk medical conditions. JAMA Pediatr 2023;177:337-44.
Source: The Journal of Pediatrics - September 22, 2023 Category: Pediatrics Authors: Annette K. Regan Tags: Current Best Evidence Source Type: research

How Wastewater Testing Can Help Tackle America ’ s Opioid Crisis
Among the many lasting legacies of COVID-19 may be a newfound appreciation for the value of what we flush down the toilet and wash down the drain. Wastewater can be a rich source of information about infectious diseases, like COVID-19, as well as flu, respiratory syncytial virus (RSV), mpox and polio, since pathogens like viruses are shed in feces, urine and saliva, all of which is drained into sewage treatment plants. Sampling that water is a good way to screen for certain viruses, and, as more people bypass the medical system and labs in favor of testing themselves at home for things like COVID-19, health agencies lik...
Source: TIME: Health - September 21, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

In Situ Spectroscopic Detection of Large-Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening
Angew Chem Int Ed Engl. 2023 Sep 21:e202309069. doi: 10.1002/anie.202309069. Online ahead of print.ABSTRACTViroporins are small ion channels in membranes of enveloped viruses that play key roles during viral life cycles. To use viroporins as drug targets against viral infection requires in-depth mechanistic understanding and, with that, methods that enable investigations under in situ conditions. Here, we apply surface-enhanced infrared absorption (SEIRA) spectroscopy to Influenza A M2 reconstituted within a solid-supported membrane, to shed light on the mechanics of its viroporin function. M2 is a paradigm of pH-activated...
Source: Angewandte Chemie - September 21, 2023 Category: Chemistry Authors: Ronja Rabea Paschke Swantje Mohr Sascha Lange Adam Lange Jacek Kozuch Source Type: research

Review: Factors influencing parents' decisions to vaccinate children against COVID-19
CONCLUSION: This review identified critical factors affecting parents' vaccination behavior for their children. Awareness of these factors may reduce parents' COVID-19 vaccine refusal for their children and guide future planning and development of public health studies.PMID:37735055 | DOI:10.1016/j.vaccine.2023.09.020
Source: Vaccine - September 21, 2023 Category: Allergy & Immunology Authors: Haifa S Alharbi Source Type: research

Identification of γ-Fagarine as a novel antiviral agent against respiratory virus (hMPV) infection
In this study, we aim to investigate the effect of γ-Fagarine on hMPV infection and explore its underlying molecular mechanisms. Vero-E6 and 16HBE cells were used as cell models. Virus replication and microcosm character were explored in Vero-E6 cells. Then, the antiviral activities were investigated by quantitative real-time PCR (RT-qPCR), western blotting (WB), and indirect immunofluorescence assays (IFAs) in Vero-E6 and 16HBE. Potential mechanisms of γ-Fagarine related to HSPG and lysosome pH were assessed in 16HBE cells. Lastly, a virus-infected mouse model was established and antiviral assay in vivo was conducted. ...
Source: Virus Research - September 21, 2023 Category: Virology Authors: Jinhua Li Yao Zhao Ying Dai Junning Zhao Source Type: research

Bibliometric analysis of publication trends and topics of influenza ‐related encephalopathy from 2000 to 2022
ConclusionsThe research progress, hotspots, and frontiers on influenza-related encephalopathy after 2000 were described through the visualization of bibliometrics. The findings will lay the groundwork for future studies and provide a reference for influenza-related encephalopathy. Research on influenza-related encephalopathy is basically at a stable stage, and the number of research results is related to outbreaks of the influenza virus.
Source: Immunity, Inflammation and Disease - September 20, 2023 Category: Allergy & Immunology Authors: Zhengyu Zhang, Juntao Tan, Ying Li, Xiumei Zhou, Jianhua Niu, Jun Chen, Hongfeng Sheng, Xiaoxin Wu, Yuan Yuan Tags: ORIGINAL ARTICLE Source Type: research

Efficient trapping and destruction of SARS-CoV-2 using PECO-assisted Molekule air purifiers in the laboratory and real-world settings
Ecotoxicol Environ Saf. 2023 Sep 18;264:115487. doi: 10.1016/j.ecoenv.2023.115487. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted human-to-human via aerosols and air-borne droplets. Therefore, capturing and destroying viruses from indoor premises are essential to reduce the probability of human exposure and virus transmission. While the heating, ventilation, and air conditioning (HVAC) systems help in reducing the indoor viral load, a targeted approach is required to effectively remove SARS-CoV-2 from indoor air to address human exposure concerns. The present study...
Source: Ecotoxicology and Environmental Safety - September 20, 2023 Category: Environmental Health Authors: Arpan Acharya Kerri Surbaugh Michellie Thurman Chatura Wickramaratne Philip Myers Rajat Mittal Kabita Pandey Elizabeth Klug Sarah J Stein Ashley R Ravnholdt Vicki L Herrera Danielle N Rivera Paul Williams Joshua L Santarpia Ajeet Kaushik Jaspreet S Dhau S Source Type: research

Evaluation the effect of dietary vitamin E, sesamin and thymoquinone bioactive compounds on immunological response, intestinal traits and MUC-2 gene expression in broiler Japanese quails ( < em > Coturnix japonica < /em > )
Anim Biotechnol. 2023 Sep 20:1-11. doi: 10.1080/10495398.2023.2259437. Online ahead of print.ABSTRACTThe current study was performed to determine the effect of dietary vitamin E, sesamin and thymoquinone bioactive lignans derived from sesame and black seed on immunological response, intestinal traits and Mucin2 gene expression in broiler quails. Three hundred and fifty (one days-old) quails were allotted to seven dietary treatments with five replicates as an experimental randomized design study. Treatments were basal diet as a control, control +100 and +200 mg of vitamin E, sesamin and thymoquinone per each kg of diet resp...
Source: Animal Biotechnology - September 20, 2023 Category: Biotechnology Authors: Yaser Rahimian Farshid Kheiri Mostafa Faghani Source Type: research

Southern Hemisphere Outcomes Support Flu Vaccine Effectiveness
The 2023 flu vaccine reduced the risk of influenza-related hospitalizations by about 52% in the Southern Hemisphere, where the flu season typically spans March through September, according to data from 2780 patients who were hospitalized with severe acute respiratory infections in 5 countries.
Source: JAMA - Journal of the American Medical Association - September 20, 2023 Category: General Medicine Source Type: research

Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research

Geospatial Distribution of Racial Disparities in Influenza Vaccination in Nursing Homes
This study aimed to assess the distribution of racial disparities in influenza vaccination between White and Black short-stay and long-stay nursing home residents among states and hospital referral regions (HRRs).
Source: Journal of the American Medical Directors Association - September 19, 2023 Category: Health Management Authors: Joe B.B. Silva, Chanelle J. Howe, John W. Jackson, Barbara H. Bardenheier, Melissa R. Riester, Robertus van Aalst, Matthew M. Loiacono, Andrew R. Zullo Tags: Original Study Source Type: research

NIH Begins Human Trials of ' Universal ' Flu Vaccine NIH Begins Human Trials of ' Universal ' Flu Vaccine
The National Institutes of Health has begun an early stage study on its experimental vaccine targeting six strains of influenza virus.Reuters Health Information
Source: Medscape Medical News Headlines - September 18, 2023 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Do both anticipated relief and anticipated regret predict decisions about influenza vaccination?
CONCLUSIONS: Results suggest that, regardless of valence, counterfactual emotions predict vaccination intention and, indirectly, behaviour. Furthermore, participants may differ in their sensitivity to the anticipation of positive versus negative counterfactual emotions. These findings may permit more precise targeting of interventions to increase vaccine uptake.PMID:37722923 | DOI:10.1111/bjhp.12691
Source: British Journal of Health Psychology - September 18, 2023 Category: Psychiatry & Psychology Authors: Sara Lorimer Teresa McCormack Christoph Hoerl Matthew Johnston Sarah R Beck Aidan Feeney Source Type: research